Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin

Generic Name

Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin

Therapeutic Class: Drugs used in Vaginal and Vulval condition

Indications:
This combination is indicated in-

• Vaginal trichomoniasis
• Vaginal leucorrhoeas
• Mixed vaginal infections (Fungal or Bacterial).

Presentation:

Each vaginal suppository contains-

• Metronidazole BP 200 mg
• Neomycin Sulphate BP 35000 IU
• Polymyxin B Sulphate BP 35000 IU
• Nystatin BP 100000 IU.

Description:
Metronidazole, a nitroimidazole, is active against various anaerobic bacteria and protozoa. Nystatin is a polyene antibiotic with antifungal activity. Neomycin is an aminoglycoside. It is bactericidal and active against some gram-positive and gram-negative organisms. Polymyxin is active against gram-negative organisms including Pseudomonas aeruginosa.

Dosage & Administration:
One suppository in the vagina at bedtime for 12 days or as directed by the physician.

Contraindications:
Contraindicated to the patients who are hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate, and Nystatin.

Side Effects:
Skin rash, urticaria may occur rarely.

Pregnancy & Lactation:
Caution should be practiced in pregnancy and lactation.

Precautions & Warnings:
Caution should be taken in case of renal impairment.

Storage:
Store in a cool and dry place, away from light & children.

• Take medicine as advised by the doctor or pharmacist.