Generic Name
Tolperisone & LidocaineTherapeutic Class: Centrally Acting Skeletal Muscle Relaxants, Locally acting Skeletal Muscle Relaxants
Indications:
Increased tone of skeletal muscles due to organic neurological disorders (e.g. injury of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis, etc.), muscular hypertension, muscular spasm, muscular contracture, rigidity, spinal automatism and discopathy, obliterative vascular diseases (obliterative arteriosclerosis, diabetic angiopathy, obliterative thromboangitis, Raynaud's disease, diffuse scleroderma) and disorders due to injured innervation of the vessels (acrocyanosis, intermittent angioneurotic dysbasia). In individual cases, post-thrombotic venous and lymphatic circulation disorders, crural ulcer.
Presentation:
Each 1 ml ampoule contains Tolperisone HCl INN 100 mg and Lidocaine HCl USP 2.5 mg.
Increased tone of skeletal muscles due to organic neurological disorders (e.g. injury of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis, etc.), muscular hypertension, muscular spasm, muscular contracture, rigidity, spinal automatism and discopathy, obliterative vascular diseases (obliterative arteriosclerosis, diabetic angiopathy, obliterative thromboangitis, Raynaud's disease, diffuse scleroderma) and disorders due to injured innervation of the vessels (acrocyanosis, intermittent angioneurotic dysbasia). In individual cases, post-thrombotic venous and lymphatic circulation disorders, crural ulcer.
Presentation:
Each 1 ml ampoule contains Tolperisone HCl INN 100 mg and Lidocaine HCl USP 2.5 mg.
Description:
Tolperisone Hydrochloride is a centrally acting muscle relaxant. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation, and reduces pain.
Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby affecting local anesthetic action.
Dosage & Administration:
The usual dose is one ampoule twice daily by intramuscularly. Injection should be given slowly.
Accordingly to age and symptom, the dosage may be changed.
Side Effects:
Sometimes, muscular weakness, headache, nausea, vomiting, and rarely hypersensitivity reactions may occur as side effects.
Precautions:
In the case of children, the prescribed dose and duration of treatment should closely be observed.
Use in Pregnancy & Lactation:
Tolperisone hydrochloride should be used in pregnancy according to the physician's advice. Tolperisone hydrochloride should not be used during breast-feeding.
Overdose:
In the event of overdosage, supportive therapy may be substituted.
Tolperisone Hydrochloride is a centrally acting muscle relaxant. It effectively reduces muscular hypertonicity, improves peripheral blood flow by vasodilatation, and reduces pain.
Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby affecting local anesthetic action.
Dosage & Administration:
The usual dose is one ampoule twice daily by intramuscularly. Injection should be given slowly.
Accordingly to age and symptom, the dosage may be changed.
Side Effects:
Sometimes, muscular weakness, headache, nausea, vomiting, and rarely hypersensitivity reactions may occur as side effects.
Precautions:
In the case of children, the prescribed dose and duration of treatment should closely be observed.
Use in Pregnancy & Lactation:
Tolperisone hydrochloride should be used in pregnancy according to the physician's advice. Tolperisone hydrochloride should not be used during breast-feeding.
Overdose:
In the event of overdosage, supportive therapy may be substituted.
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