Prednisolone Acetate (Ophthalmic): Uses,Dosage,Side Effects

Generic Name

Prednisolone Acetate Eye Drops
Therapeutic Class: Ophthalmic (Glucocorticoids)

Indications:
Prednisolone Acetate is indicated for the treatment of steroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe.

Presentation:
Prednisolone Acetate Sterile Ophthalmic Suspension: Each ml sterile Ophthalmic Suspension contains Prednisolone Acetate USP 10 mg.

Description:
Prednisolone Acetate is a glucocorticoid. It inhibits edema, inflammation, capillary proliferation, deposition of collagen. Therefore, swelling and pain of inflammatory conditions are decreased.

Dosage & Administration:
Instill one drop into the conjunctival sac two to four times daily. During the initial 24 to 48 hours, the dosing frequency may be increased if necessary. Care should be taken not to discontinue the therapy before completing the course.
Pediatric Use: Safety and effectiveness in pediatric patients have not been established.

Side Effects:
Elevation of intraocular pressure (IOP) with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation and delayed wound healing.
Fungal and viral infections of the cornea are particularly may develop coincidentally with long-term applications of steroid.

Precautions:
Shake the bottle well before use. Prolonged use of corticosteroids may result in damage to the optic nerve and defects in vision. If this product is used for a longer period of time, intraocular pressure should be routinely monitored.

Use in Pregnancy & Lactation:
Pregnancy: Prednisolone Acetate is pregnancy category C. So, this drug should be used during pregnancy only if clearly needed.
Lactation: It is not known whether topical administration of corticosteroids would result in sufficient systemic absorption to produce detectable quantities in human milk. Because many drugs are excreted in human milk, caution should be exercised when Prednisolone Acetate is administered to a nursing woman.

Interaction:
No significant drug interactions have been reported.

Overdose:
A one-time accidental overdose of Prednisolone Ophthalmic Suspension generally will not cause acute problems. Long-time overdose may show general side effects. In accidental overdose sufficient water should be taken to dilute the medication.

Storage:
Store in a cool, dry place and protect from light.
Keep out of the reach of children.
Protect from freezing.
Shake well before using.