Vitamin B1, B6 & B12: Uses,Dosage,Side Effects

Generic Name
Vitamin B1, B6 & B12

Specific combined vitamin preparations

Indications:

This combination could also be used in-

• Chronic pains like sciatica
• Lumbago
• Trigeminal neuralgia
• Facial paralysis
• Optic neuritis
• As well as neuropathy & cardiac complications. Besides these, this mix could also be utilized in the deficiency of those vitamins.

Each film-coated tablet contains-

Vitamin B1 (Thiamine Mononitrate) 100 mg

Vitamin B6 (Pyridoxine Hydrochloride) 200 mg

Vitamin B12 (Cyanocobalamin) 200 microgram.

Each 3 ml ampoule contains-

Thiamine Hydrochloride (Vitamin B1) 100 mg

Pyridoxine Hydrochloride (Vitamin B6) 100 mg

Cyanocobalamin (Vitamin B12) 1000 mcg.

Pharmacology:

This is a combined preparation of vitamin B1 (Thiamine Mononitrate), vitamin B6 (Pyridoxine Hydrochloride), and vitamin B12 (Cyanocobalamin). These vitamins play an important role as co-enzyme within the metabolism of systema nervosum. supports the regeneration of nerve fibers and medullary sheath by activation of the neuron metabolism and therefore the natural repair mechanism.

Dosage & Administration:

Tablets: 1 to three tablets per day or as directed by the physician.

Injection: Ampules are preferably injected intramuscularly (deep intragluteal). In severe cases, 1 ampoule daily until the acute symptoms subside. For milder cases and follow up therapy 2 to three ampoules per week.

Interaction:

Vitamin B6 (Pyridoxine Hydrochloride) reduces the therapeutic effect of Levodopa but it doesn't occur if a dopa decarboxylase inhibitor is additionally given. Neomycin, Chloramphenicol, Aminosalicylic acid & H2 receptor antagonists may reduce vitamin B12 absorption.

Contraindications:

It shouldn't be utilized in patients with known hypersensitivity to Thiamine, Cobalt, or the other component of those preparations.

Side Effects:

Very rarely allergy and sensitivity disturbance may occur.

Pregnancy & Lactation:

No risks became known related to the utilization of this mix during pregnancy at the recommended dosage. vitamin B1, B6 & B12 are secreted into the breast milk but risks of overdose for the infant aren't known.

Precautions & Warnings:

It should be avoided just in case of hypersensitivity to Thiamine, Cobalt, or the other component of those preparations. Cyanocobalamin shouldn't tend before a diagnosis has been fully established due to the masking symptoms of subacute degeneration of the medulla spinalis.

Storage:

Keep in a dry place far away from light and warmth. exclude the reach of Children's.

Brand Names

Brand Name	Company	Strength
Neobion	Aristopharma Ltd.	100 mg+200 mg+200 mcg
Neurocare	Beximco Pharmaceuticals Ltd.	100 mg+200 mg+200 mcg
Vitabion	Incepta Pharmaceuticals Ltd.	100 mg+200 mg+200 mcg
Neuro-B	Square Pharmaceuticals Ltd.	100 mg+200 mg+200 mcg
Myelin	Opsonin Pharma Ltd.	100 mg+200 mg+200 mcg
B126	Popular Pharmaceuticals Ltd.	100 mg+200 mg+200 mcg